职 称：校聘副教授
学 历：博士
E-mail: 20250117@hbut.edu.cn
研究方向：食品大分子结构与功能
教育经历：
2019/07-2023/03，浙江大学，食品科学，博士
2015/09-2018/06，贵州大学，发酵工程，硕士
2011/09-2015/06，长江大学，食品科学与工程，学士
工作经历：
2018/07-2019/07，贵州大学明德学院，健康管理系，讲师
2023/12-2024/12，法国国家农业食品与环境研究院，博士后
2023/05-2025/12，浙江大学，生物系统工程与食品科学学院，学科博士后
荣获奖励：
2023年获浙江省优秀毕业生
2023年浙江省优秀博士论文提名
研究课题：
1. 国家自然科学基金青年基金C类, 蓝光基于Ca2+/CaM信号途径调控中国美味蘑菇合成多糖的机制研究, 2026.01-2028.12,主持;
2. 浙江省博士后择优资助项目, 深共晶溶剂转化竹渣废弃物合成高等真菌蛋白的关键技术及应用, 2024.01-2026.12,主持
研究成果：
发表论文
1. Hongyun Lu, Yejiayi Lv, Siyu Liu, Peng Xu, Ying Shi, Qihe Chen*. Novel nanocellulose/carrageenan oral hydrophobic aerogel as fat digestion inhibitor with high performance and rapid fat-lowering bioactivity. Bioactive Materials, 2025, 58:574-589. (1区Top, IF:20.3)
2. Hongyun Lu, Siyu Liu, Ying Shi, Qihe Chen*. Efficient delignification of sugarcane bagasse by fenton oxidation coupled with ultrasound-assisted NaOH for biotransformation from Agaricus sinodeliciosus var. Chaidam. Chemical Engineering Journal, 2022, 448, 137719. (1区Top, IF:13.2)
3. Hongyun Lu, Hanghang Lou, Tianyu Wei, Zhengjie Liu, Yingchun Jiao, Qihe Chen*. Ultrasound enhanced production of mycelia and exopolysaccharide by Agaricus bitorquis (Quel.) Sacc. Chaidam. Ultrasonics Sonochemistry, 2020, 64, 105040. (1区Top, IF:9.7)
4. Hongyun Lu, Siyu Liu, Shenliang Zhang, Jicheng Chen*, Qihe Chen*. Suppression of Alzheimer's disease by Agaricus sinodeliciosus var. Chaidam exopolysaccharide with Amyloid-β clearance activity via gut microbiota- metabolite regulation. International Journal of Biological Macromolecules, 2025, 305, 141048. (1区Top, IF:8.5)
5. Hongyun Lu, Hanghang Lou, Jingjin Hu, Zhengjie Liu, Qihe Chen*. Macrofungi: A review of cultivation strategies, bioactivity, and application of mushrooms. Comprehensive Reviews in Food Science and Food Safety, 2020, 19 (5), 2333-2356. (1区Top, IF:14.1, 他引126次)
6. Bijie Wang, Ying Shi, Hongyun Lu**, Qihe Chen *. A critical review of fungal proteins: Emerging preparation technology, active efficacy and food application. Trends In Food Science & Technology, 2023, 141. (1区Top, IF:15.4）
7. Hongyun Lu, Jicheng Chen, Ying Shi, Wei Wang*, Qihe Chen*. Mannose-rich exopolysaccharide from Agaricus sinodeliciosus var.: Purification, chemical characterization, and neuroprotective activity. Food frontiers, 2023, 4(3): 1523-1541. (1区, IF:6.9)
8. Hongyun Lu, Tianyu Wei, Hanghang Lou, Xiaoli Shu*, Qihe Chen*. A critical review on communication mechanism within plant-endophytic fungi interactions to cope with biotic and abiotic stresses. Journal of Fungi, 2021, 7(9), 719. (2区, IF:4, 高被引热点文章, 他引120次)
9. Hongyun Lu, Wen Zhao, Wei-Hsien Liu, Ting Sun, Hanghang Lou, Tianyu Wei, Wei-Lian Hung*, Qihe Chen*. Safety Evaluation of Bifidobacterium lactis BL-99 and Lacticaseibacillus paracasei K56 and ET-22 in vitro and in vivo. Frontiers in Microbiology, 2021, 12, 686541. (2区, IF:4.5)
10. Hongyun Lu, Siyu Liu, Shengliang Zhang, Qihe Chen*. Light irradiation coupled with exogenous metal ions to enhance exopolysaccharide synthesis from Agaricus sinodeliciosus ZJU-TP-08 in liquid fermentation. Journal of Fungi, 2021, 7(11), 992. (2区, IF:4)
11. Hongyun Lu, Zhihua Jiao, Yingchun Jiao, Wei Wang, Qihe Chen*. Phenolic acids-rich fractions from Agaricus bitorguis (Quél.) Sacc. Chaidam mycelia modulate hypoxic stress on hypoxia-damaged PC12 cells. Molecules, 2019, 24, (21) 4845. (2区, IF:4.6)
12. Hongyun Lu, Qin Shu, Hanghang Lou, Qihe Chen*. Mitochondria-mediated programmed cell death in Saccharomyces cerevisiae induced by betulinic acid is accelerated by the deletion of PEP4 gene. Microorganisms, 2019, 24, (21) 538. (2区, IF:4.2)
13. Hongyun Lu, Keqin Ying, Ying Shi, Donghong Liu *, and Qihe Chen*. Bioprocessing by decellularized scaffolds biomaterials in cultured meat: A Review. Bioengineering-basel, 2023, 9(12) 787. (2区, IF:3.9)
14. Hongyun Lu, Shengliang Zhang, Jinling Wang*, Qihe Chen*. A Review on polymer and lipid-based nanocarriers and its application to nano-pharmaceutical and food-based systems. Frontiers in Nutrition, 2021, 8, 783831. (2区, IF:5.1, 他引158次，高被引文章)
发明专利
1.陈启和, 芦红云, 娄行行.一种百香果发酵型果饮及其制备工艺. 中国发明专利授权号: ZL202110624854.7. 授权日: 2022-09-06
2.陈启和, 芦红云, 张圣良.一种柴达木中国美味蘑菇及其应用. 中国发明专利授权号: ZL202111260598.4. 授权日: 2022-09-06
