职称：副教授
学历：博士
邮箱：xiaojun@hbut.edu.cn
研究方向：结构生物学，细菌免疫
学习、工作经历
2025年12月获武汉大学药学博士学位
2025.12—2026.07，华中农业大学，博后
2026.08—今，湖北工业大学，副教授
科研项目
1. 国家自然科学基金青年科学基金项目C类（32600060）, 2027.01-2029.12，30万，主持；
2. 中国科协青年人才托举工程博士生专项计划，2025.01-2026.12，4万，主持；
3. 国家重点研发计划（2022YFA0912200），2022-2027，1685万，参与。
学术成果（#并列第一作者，*通讯作者）
1. Xuejun Rong#, Jun Xiao#, Xinyuan Zhao#, Yan Yan#, Jing Li#, Yifan Chen, Yihua Fan, Zhichao Liu, Yue Cao, Fan Chen, Rui Cheng, Xionglue Wang*, Longfei Wang*, and Bin Zhu*. DNA polymerization activates RNA cleavage of a reverse transcriptase–like antiviral enzyme. Science. 2026.
2. Jun Xiao, Yan Yan, Jing Li, Greater Kayode Oyejobi, Dongyang Lan, Bin Zhu*, Zhiming Wang*, Longfei Wang*. Structures and mechanism of E2-CBASS anti-phage system. mLife. 2026.
3. Yan Yan#, Jun Xiao#, Fengtao Huang#*, Wei Xian#, Bingbing Yu, Rui Cheng, Hui Wu, Xueling Lu, Xionglue Wang, Wenjing Huang, Jing Li, Greater Kayode Oyejobi, Carol V. Robinson, Hao Wu, Di Wu*, Xiaoyun Liu,* Longfei Wang*, Bin Zhu*. Phage defence system CBASS is regulated by a prokaryotic E2 enzyme that imitates the ubiquitin pathway. Nature Microbiology. 2024.
4. Jun Xiao, Bing Peng, Zhaowei Su, Ankun Liu, Yajing Hu, Christopher T. Nomura, Shouwen Chen*, Qin Wang*. Facilitating protein expression with portable 5’-UTR secondary structures in Bacillus licheniformis. ACS Synthetic Biology. 2020.
5. Jing Li#, Rui Cheng#, Zhiming Wang#, Wuliu Yuan, Jun Xiao, Xinyuan Zhao, Xinran Du, Shiyu Xia, Lianrong Wang, Bin Zhu*, Longfei Wang*. Structures and activation mechanism of Gabija anti-phage system. Nature. 2024.
6. Xueling Lu, Jun Xiao, Longfei Wang, Bin Zhu*, Fengtao Huang*. The nuclease-associated short prokaryotic Argonaute system nonspecifically degrades DNA upon activation by target recognition. Nucleic Acids Research. 2023.
7. Manyu Zhang#, Jing Song#, Jun Xiao, Jingjie Jin, Christopher T. Nomura, Shouwen Chen*, Qin Wang*. Engineered multiple translation initiation sites: a novel tool to enhance protein production in Bacillus licheniformis and other industrially relevant bacteria. Nucleic Acids Research. 2022.
8. Siqi Zuo, Jun Xiao, Yuan Zhang, Xiaodong Zhang, Christopher T. Nomura, Shouwen Chen*, Qin Wang*. Rational design and medium optimization for shikimate production in recombinant Bacillus licheniformis strains. Process Biochemistry. 2018.
