张艳

职称：副教授

学历：博士

E-mail: yzhang@hbut.edu.cn

研究方向：功能化复合水凝胶的结构设计及其在食品安全中的应用

教育经历：2013/07-2018/06，华中科技大学，材料物理与化学，博士

2009/09-2013/06，长江大学，化学，学士

工作经历：2018/07-2022/05，华中科技大学同济医学院附属协和医院，临床医学，博士后

2024/04-2025/04，南洋理工大学，化学、化工与生物工程学院，访问学者

2022/06-至今，湖北工业大学，生命科学与健康学院，食品科学与技术

荣获奖励：

2023年湖北省优秀博士后追踪计划

2024年武汉英才青年项目

2025年湖北省相关人才项目

研究课题：

1.国家自然科学基金青年项目 高选择性硫化氢微电极在评估结直肠癌进展中的应用 2022.01-2024.12 主持；

2.湖北省国际科技交流合作 植物蛋白质组装体模拟肉类肌原纤维结构力学特性研究 2022.09-2024.09 主持；

3. 中国博士后科学基金面上项目 多级碳管阵列微电极的制备及其在癌细胞检测中的应用 2019.05-2021.12 主持；

4. 湖北工业大学博士启动基金 金属有机框架衍生微电化学传感器的构建及在食品安全检测中的应用 主持；

5. 武汉英才青年项目 功能化水凝胶微传感器应用于谷类食品安全分析 2025.01-2026.12 主持；

6. 111计划国际合作项目 功能集成型水凝胶微球的构建及其食源性致病菌检测机制研究 2024.01-2026.12 主持；

研究成果：

[1] Yan Zhang, Xiaohua He, Nan Liu, Danni Peng, Jian Xiao, Duoxia Xu, Nan Yang* Smartphone-assisted dual-mode portable sensor for highly sensitive detection of ochratoxin A in foods. Talanta 300 (2026) 129220.

[2] Yan Zhang#*, Hehaoming Zheng, Xiaohua He, Danni Peng, Jian Xiao, Yunxia Jin*. MOF-derived nanozyme-encapsulated alginate microspheres enable smartphone-based total antioxidant capacity quantification. Microchemical Journal 2025,218,115359.

[3] Yan Zhang, Danni Peng, Xiaohua He, Hehaoming Zheng, Jian Xiao, Duoxia Xu, Nan Yang*. Blueberry anthocyanins-functionalized hydrogel labels for smartphone-assisted real-time visual freshness monitoring of perishable proteins. Talanta 2026, 297, 128813.

[4] Qin Haowen, Zheng Hehaoming, He Xiaohua , Peng Danni, WuYing, XiaoJian, Zhang Yan* Functional metal-organic frameworks derived-nanozyme integrated sodium alginate hydrogel microspheres for visual total antioxidant capacity detection in foods. Chemical Engineering Journal 2025,513,162756.

[5] Zhang Yan, Qin Haowen, Peng Danni, Han Minghui, Jian Xiao, Ying Wu, Nan Yang. Au confined covalent organic frameworks nanoenzyme integrated with sodium alginate microsphere for portable colorimetric tannic acid detection. International Journal of Biological Macromolecules 2025.

[6] Yan Zhang, Minghui Han, Danni Peng, Hehaoming Zheng, Haowen Qin, Jian Xiao, Ying Wu, Nan Yang. A self-supported electrochemical immunosensor based on Cu₂O/CuO@AuNPs heterostructures for sensitive and selective detection of ochratoxin A in food. Talanta 2025, 287, 127657.

[7] Yan Zhang, Tao Lin, Minghui Han, Min Hu, Yun Xu, Wei Huang, Fei Xiao, Anshun Zhao. A microelectrode electrochemical sensing platform based on heteroatoms doped carbon nanotubes arrays with peroxidase-like activity for in-situ detection in live cell. Analytica Chimica Acta 2024, 1297, 342386.

[8] Yan Zhang, Minghui Han, Danni Peng, Haowen Qin, Hehaoming Zheng, Jian Xiao, Nan Yang. MOF-derived high-density carbon nanotubes “tentacle” with boosting electrocatalytic activity for detecting ascorbic acid. Talanta 2024, 279, 126578.

[9] Zhang Yan, Xiao Jian, Lv Qiying, Wang Lu, Dong Xulin, Muhammad Asif, Ren Jinghua, He Wenshan, Sun Yimin, Xiao Fei*, Wang Shuai* 3D heteroatom-doped graphene-wrapped flexible carbon fiber microsensor for real-time hydrogen peroxide detection in live cancer cells . Applied Surface Science 2023, 611, 155655.

[10] Zhang Yan, Qin Haowen, Han Minghui, Xiao Jian, Yang Nan. Electrochemical sensor based on three-dimensional skeleton/skin ink for the ultrasensitive detection of dopamine released from neural cells. Microchemical Journal 2023, 193, 109199.

[11] Yang Wenbo, Hu Hongzhi, Pan Qing, Deng Xiangyu, Zhang Yan*, Shao Zengwu*. In Iron-polydopamine coated multifunctional nanoparticle SiO₂@PDA/Fe³⁺-FA mediated low temperature photothermal for chemodynamic therapy of cisplatin-insensitive osteosarcoma. Materials & Design 2023, 227, 111785.

[12] Zhang Yan # , Chi Kai, Xiao Jian, Xu Yangyang, Zhao Anshun, Xu Yun, Sun Yimin, Xiao Fei*, Wang Shuai* Coral-like hierarchical structured carbon nanoscaffold with improved sensitivity for biomolecular detection in cancer tissue. Biosensors and Bioelectronics 2020, 150, 111924.

[13] Zhang Yan # , Lv Qiying, Chi Kai, Li Qilin., Fan Huilin, Cai Bo, Xiao Fei*, Wang Shuai*, Wang Zheng*, Wang Lin* Hierarchical porous carbon heterojunction flake arrays derived from metal organic frameworks and ionic liquid for H₂O₂ electrochemical detection in cancer tissue. Nano Research 2021,14, 1335.

[14] Zhang Yan , Xiao Jian, Lv Qiying, Wang Lu, Dong Xulin, Muhammad Asif, Ren Jinghua, He Wenshan, Sun Yimin, Xiao Fei*, Wang Shuai* 3D heteroatom-doped graphene-wrapped flexible carbon fiber microsensor for real-time hydrogen peroxide detection in live cancer cells. Applied Surface Science 2023, 611, 155655.

[15] Zhang Yan, Qin Haowen , Han Minghui, Xiao Jian *, Yang Nan *. Electrochemical sensor based on three-dimensional skeleton/skin ink for the ultrasensitive detection of dopamine released from neural cells. Microchemical Journal 2023, 193, 109199.

[16] Xi Jiangbo, Zhang Yue, Ye Ting, Xiao Jian, Fang Jun, Han Minghui, Zhao Anshun, Yan Zhang* Selfsupported electrochemical sensor based on uniform palladium nanoparticles functionalized porous graphene flm for monitoring H₂O₂ released from living cells. Analytical and Bioanalytical Chemistry 2024, 416:6995-7006.

[17] Liu Junyao, Chen Guangqin,Xiao Jian, Zhang Yan*, Co-P/Fe₃O₄ composite film on nickel foam prepared by one-step electrodeposition for efficient overall water splitting. International Journal of Hydrogen Energy 2024, 62, 803-811.

[18] Li Qilin # , Zhang Yan # , Fan Huilin, Gong Yuji, Xu Yun, Lv Qiying, Xu Y.unruo, Xiao Fei*, Wang Shuai*, Wang Zheng*, Wang Lin* In vitro and in vivo detection of lactate with nanohybrid-functionalized Pt microelectrode facilitating assessment of tumor development. Biosensors and Bioelectronics 2021, 191, 113474.

[19] Xiao Jian*, Wang Yongjian, Liu Junyao, Yang Yang, Zhang Yan* , Luo Xiaogang*. Hierarchical Ni/Ni₄Mo nanosheets array on carbon fiber as a bifunctional electrocatalyst for urea-oxidation-assisted water splitting. International Journal of Hydrogen Energy 2023, 2024, 51, 982-992.

[20] Xiao Jian, Qiao Rongzhi, Zhang Yan*, Luo Xiaogang* Porous Co₂P film coated on carbon fiber as highly performance electrocatalyst toward overall water splitting. International Journal of Hydrogen Energy 2021, 6, 31-40.

[21] Dai Jiahao#, Cai Bo#, Zhang Yan#, Zhao Shukun, Zhao Xingzhong, Wang Guobin*, Wang Lin*, and Wang Zheng*.Gelatin-coated ZnO array nanoplatform for sapture, drug resistance identification, and recovery of circulating tumor cells. Advanced Material Technologies 2023, 2201584.

[22] Zhang Yan #, Xiao Jian, Sun Yimin, Wang Lu, Dong Xulin, Ren Jinghua, He Wenshan, Xiao Fei* Flexible nanohybrid microelectrode based on carbon fiber wrapped by gold nanoparticles decorated nitrogen doped carbon nanotube arrays: In situ electrochemical detection in live cancer cells. Biosensors and Bioelectronics 2018, 100, 453-461.

[23] Zhang Yan #, Xiao Jian, Lv Qiying., Wang Lu, Dong Xulin, Muhammad Asif, Ren Jinghua, He Wenshan, Sun Yimin, Xiao Fei*, Wang Shuai* In situ electrochemical sensing and real-time monitoring live cells based on freestanding nanohybrid paper electrode assembled from 3D functionalized graphene framework. ACS Applied Material & Interfaces 2017, 44, 38201-38210.

[24] Zhang Yan#, Xiao Jian #, Lv Qiying, Wang Shuai* Self-supported transition metal phosphide based electrodes as high-efficient water splitting cathodes. Frontiers of Chemical Science and Engineering 2018, 12, 494.

专利

[1] 王琳，王征，张艳，李琪琳。一种微针电极的制备及其应用。专利申请号：202011105662.7（已授权）。

[2] 肖菲，张艳，王帅，王露，肖健。一种三维柔性电极或三维柔性催化剂及它们的制备与应用。专利号：ZL201610848339.6（已授权）。

[3] 肖菲，张艳，肖健，王露。一种金纳米花修饰的离子液体功能化石墨烯纸电极及其制备方法和应用。专利号：ZL201611174558.7（已授权）。

[4] 肖菲，张艳，肖健，王露。一种多元素掺杂的三维多孔石墨烯气凝胶的制备方法。专利号：ZL201611207329.0（已授权）。

[5] 肖菲，许云，张艳，赵安顺。一种多元素掺杂的石墨烯纤维及其制备和应用。专利号：201910945024.7 (已授权)。

[6] 张艳，韩明慧，彭丹妮，何小华。一种基于Au修饰的Cu₂O/CuO异质结构的自支撑电化学免疫传感器的制备方法和应用。专利号：2024227626247。

[7] 肖菲，董旭林，张艳，高若涵。多元素掺杂碳纳米管阵列修饰碳纤维及其制备方法与应用。专利号：ZL201810805364.5 (已授权)。

[8] 肖菲，徐齐，张艳，董旭林。一种双纳米酶修饰碳纤维复合材料、其制备方法和应用。专利号：ZL 201810135110.7 (已授权)。

[9] 王琳,王征,李琪琳,张艳,郭红莲。空心金碳纳米球/犬尿氨酸酶双重修饰的铂微电极及其制法和应用。专利号：ZL 202311467841.9 (已授权)。