职称：讲师
学历：博士
E-mail：20260040@hbut.edu.cn
基本情况：
2015.09 - 2019.06 武汉工程大学，生物工程，工学学士
2019.09 - 2026.06 江南大学，发酵工程，工学博士
2025.02 - 2026.02 The University of Auckland，联合培养博士
2026.08 - 至今 湖北工业大学，生命科学与健康工程学院，讲师
研究方向：基因表达调控元件的智能设计；微生物合成生物学与代谢调控；生物传感器与高通量筛选
研究成果：
1. Xuan Zhou, Renxu Feng, Nana Ding, Wenyan Cao, Yang Liu*, Shenghu Zhou*, Yu Deng*. Deep learning guided programmable design of Escherichia coli core promoters from sequence architecture to strength control. Nucleic Acids Research. 2025, 53: gkaf863. (IF=15.0)
2. Xuan Zhou, Wenyan Cao, Chao Huang, Xiaojuan Zhang, Shenghu Zhou*, Yu Deng*. Designing prokaryotic gene expression regulatory elements: From genomic mining to artificial intelligence-driven generation. Biotechnology Advances. 2025, 76: 108781. (IF=14.1)
3. Xuan Zhou, Ning Ding, Shenghu Zhou*, Yu Deng*. AI-guided design and predictive modeling of synthetic Escherichia coli promoters through comprehensive −10/−35 box engineering. ACS Synthetic Biology. 2026, 15(2): 728-739. (IF=4.5)
4. Shun Li#, Xuan Zhou#, Ye Chen, Guohui Li*, Yu Deng*. Precision quantification and rational regulation of protein expression with bicistronic cassette for efficient biotin production. Journal of Agricultural and Food Chemistry. 2025, 73(11): 6854-6866. (IF=6.7)
5. Nana Ding#, Lei Sun#, Xuan Zhou#, Linpei Zhang, Yu Deng*, Lianghong Yin*. Enhancing glucaric acid production from myo-inositol in Escherichia coli by eliminating cell-to-cell variation. Applied and Environmental Microbiology. 2024, 90(6): e0014924. (IF=4.2)
6. Wenyan Cao, Xuan Zhou, Chao Huang, Shenghu Zhou*, Yu Deng*. Developing PhoR-PhoB-based biosensor by directed evolution for application in ultralow inorganic phosphorus detection. ACS Sensors. 2025, 10(9): 6489–6500. (IF=10.9)
7. Wenyan Cao, Chao Huang, Xuan Zhou, Shenghu Zhou*, Yu Deng*. Engineering two-component systems for advanced biosensing: From architecture to applications in biotechnology. Biotechnology Advances. 2024, 75: 108404. (IF=14.1)
8. Yin Mao, Chao Huang, Xuan Zhou, Runhua Han, Yu Deng, Shenghu Zhou. Genetically encoded biosensor engineering for application in directed evolution. Journal of Microbiology and Biotechnology. 2023, 33(10): 1257–1267. (IF=3.4)
9. Shenghu Zhou, Chao Huang, Qianni Li, Xuan Zhou, Yu Deng. Engineering thermophilic glucokinase with enhanced activity and expression via self-assembling amphipathic peptide fusion and biosensor-based high-throughput screening. Sensors and Actuators B: Chemical. 2025: 139201. (IF=8.3)
