职 称：教授
学 历：博士
E-mail: zjliu@hbut.edu.cn
研究方向：合成生物学、代谢工程、食品生物技术
学习、工作经历：
武汉大学博士，教授，博士生导师，湖北省相关人才项目入选者，先后在Bioresource Technology、Journal of Agricultural and Food Chemistry和LWT等杂志上发表SCI论文四十余篇。主持国家自然科学基金和湖北省重点研发等科研项目十余项、校企合作项目十余项。
2017/02-至今,湖北工业大学，生命科学与健康工程学院，讲师、副教授、教授
荣获奖励：
1. 2021年全国大学生生命科学竞赛二等奖，指导老师。
2. 2019年国际基因工程机器大赛（iGEM）金奖，指导老师。
3. 2018年国际基因工程机器大赛（iGEM）银奖，指导老师。
社会兼职：
1. 湖北省企业“科技副总”。
2. 湖北省科技特派员。
研究课题：
1. 湖北省重点研发计划项目，100万元，2023.01-2025.12，主持。
2. 湖北省自然科学基金，5万元，2023.07-2025.06，主持。
3. 国家自然科学基金，30万元，2021.01-2023.12，主持。
4. 湖北省自然科学基金，3万元，2018.01-2019.12，主持。
5. 企业合作项目，发酵蔬菜技术开发与应用，500万元，2023.12-2028.11，主持。
6. 企业合作项目，天然产物的合成，200万元，2023.10-2024.10，主持。
7. 企业合作项目，多元醇新工艺研究，300万元，2021.09-2026.08，主持。
研究成果：
1. Yang et al. A study of antibacterial activity and mechanism of potassium cinnamate intended as a natural preservative. LWT, 2025: 117237.
2. Zheng et al. Utilization of nanoemulsion to enhance antibacterial capacity of Zanthoxylum bungeanum pericarp essential oils against foodborne pathogenic bacteria. LWT, 2024: 116657.
3. Qin et al. Antibacterial activity and mechanism of the sesquiterpene δ-cadinene against Listeria monocytogenes. LWT, 2024: 116388.
4. Chen et al. Antimicrobial activity and mechanism of α-copaene against foodborne pathogenic bacteria and its application in beef soup. LWT, 2024: 115848.
5. Kang et al. Metabolomic insights into the effect of chickpea protein hydrolysate on the freeze–thaw tolerance of industrial yeasts. Food Chemistry, 2024, 439: 138143.
6. Liu et al. Improving an Alternative Glycerol Catabolism Pathway in Yarrowia lipolytica to Enhance Erythritol Production. Yeast, 2024, 1-10.
7. Wang et al. Comparative transcriptome analysis reveals the redirection of metabolic flux from cell growth to astaxanthin biosynthesis in Yarrowia lipolytica. Yeast, 2024, 1–10.
8. Wang et al. Metabolic engineering of erythritol production from glycerol by Yarrowia lipolytica. Biotechnology and Bioprocess Engineering, 2024: 1-9.
9. Fu et al. Co-culture relationship between Zygosaccharomyces rouxii and Candida versatilis and its effect on the flavour of soy sauce. International Journal of Food Science & Technology, 2024, 59(1): 228-240.
10. Liu et al. Transcriptomics Reveals the Effect of Strain Interactions on the Growth of A. Oryzae and Z. Rouxii. Journal of Agricultural and Food Chemistry, 2023, 71(14): 5525-5534.
11. Liu et al. Analysis of the contribution of koji-making with Z. rouxiion volatile compounds of soy sauce. LWT, 2023: 114903.
12. Zhang et al. Metabolic engineering of Escherichia coli for the biosynthesis of α-copaene from glucose. Biochemical Engineering Journal, 2022, 186: 108561.
13. Liu et al. Enhancing Trans-Nerolidol Productivity in Yarrowia lipolytica by Improving Precursor Supply and Optimizing Nerolidol Synthase Activity. Journal of Agricultural and Food Chemistry, 2022, 70(48): 15157-15165.
14. Zhang et al. Effect of Lactobacillus plantarum or Enterococcus faecalis as co-inoculants with Aspergillus oryzae in koji making on the physicochemical properties of soy sauce. Journal of Food Science, 2022, 87(2): 714-727.
15. Zheng et al. A novel Fenton-like catalyst of Ag3PO4/g-C3N4: Its performance and mechanism for tetracycline hydrochloride degradation in dark. Applied Surface Science, 2022, 571: 151305.
16. Wang et al. Integrated pathway engineering and transcriptome analysis for improved astaxanthin biosynthesis in Yarrowia lipolytica. Synthetic and Systems Biotechnology, 2022, 7(4): 1133-1141.
17. Zhang et al. De novo biosynthesis of alpha-zingiberene from glucose in Escherichia coli. Biochemical Engineering Journal, 2021, 176: 108188.
18. Zhang et al. Metabolic engineering of β-carotene biosynthesis in Yarrowia lipolytica. Biotechnology letters, 2020, 42: 945-956.
19. Gao et al. Yarrowia lipolytica as a metabolic engineering platform for the production of very-long-chain wax esters. Journal of Agricultural and Food Chemistry, 2020, 68(39): 10730-10740.
20. Zong et al. Metabolic engineering of Escherichia coli for the production of neryl acetate. Biochemical Engineering Journal, 2020, 161: 107704.
21. Yao et al. Engineering oleaginous yeast Yarrowia lipolytica for enhanced limonene production from xylose and lignocellulosic hydrolysate. FEMS Yeast Research, 2020, 20(6): foaa046.
22. Liu et al. Pathway engineering and medium optimization for α-farnesene biosynthesis in oleaginous yeast Yarrowia lipolytica. Journal of Biotechnology, 2020, 319: 74-81.
23. Wang et al. Metabolic engineering of Yarrowia lipolytica for the biosynthesis of crotonic acid. Bioresource Technology, 2019, 287: 121484.
24. Zong et al. Biosynthesis of nerol from glucose in the metabolic engineered Escherichia coli. Bioresource Technology, 2019, 287: 121410.
25. Liu et al. De novo biosynthesis of antimycobacterial agent geranylgeranyl acetate from glucose. Biochemical Engineering Journal, 2019, 142: 84-88.
26. Guo et al. Metabolic engineering of Escherichia coli for production of 2-phenylethanol and 2-phenylethyl acetate from glucose. Journal of Agricultural and Food Chemistry, 2018, 66(23): 5886-5891.
27. Guo et al. Biosynthesis of advanced biofuel farnesyl acetate using engineered Escherichia coli. Bioresource Technology, 2018, 269: 577-580.
28. Peng et al. Effect of citrus peel on phenolic compounds, organic acids and antioxidant activity of soy sauce. LWT, 2018, 90: 627-635.
参编学术专著：
1. 王智文主编，《代谢工程与合成生物学（第二版）》，高等教育出版社，2023，ISBN (9787040599404)。
2. 赵学明主编，《代谢工程》，高等教育出版社，2015，ISBN (9787040417692)。
授权专利：
1. 一种利用微生物发酵生产橙花醇的方法. ZL201910182141.2。
2. 产α-古巴烯的重组酿酒酵母及其应用. ZL202210373921.7。
3. 产T-杜松醇的重组酿酒酵母及其应用. ZL202210305472.2。
